Top 10 Best Mephisto Genetics Seeds: Strain Guide

Mephisto Genetics Best Seeds Strain Guide

Explore ten of the best marijuana seed strains for sale from Mephisto Genetics–a hugely popular seedbank known for its connoisseur autoflowers. This strain guide will give you the 411 on these in-demand autoflowering genetics. All of the strains below are available to purchase online in the USA, with fast and discreet shipping to every state in the country.


Double Grape Auto

Double Grape Auto - Mephisto Genetics

Double Grape Auto is a cutting-edge F7 feminized autoflowering strain, born from the aromatic union of Sour Stomper and Grape Crinkle. This balanced 60/40 indica-sativa hybrid delivers robust trichome development and a mouthwatering grape-gas bouquet that belies its compact frame. Clocking in at nearly 37% total cannabinoids (with over 31% THC), it stakes its claim as one of the most potent autos around.

Cultivators of all skill levels will appreciate its forgiving nature—this strain flourishes with minimal fuss, responding well to gentle LST or strategic leaf-tucking. It stays petite at 22–31 inches tall over a 70–80-day cycle, making it ideal for tight spaces or Sea Of Green setups. Indoor growers should monitor odor, as its sweet-sour grape funk can become pronounced. Yields range from 90 to 120 grams per plant, reaching up to 500 grams per square meter under a 600-watt light.

The dense buds glisten with a frosty layer of resin, exuding flavors of ripe red grapes and fizzy soda on the exhale. Users report an initial cerebral uplift that melts into soothing sedation, perfect for easing aches, boosting appetite, or drifting off to sleep. High terpene levels, particularly myrcene and limonene, and resin production make it a stellar choice for extraction projects.

Flowering Time 65–70 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 90–120 g/plant

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Sour Stomper Auto

Sour Stomper Auto - Mephisto Genetics

Sour Stomper Auto is an F7 feminized automatic with equal parts indica and sativa, crafted from GrapeStomper OG and Sour Crack, undergoing careful selection by Mephisto Genetics. Its hallmark is a vivid red-grape aroma intertwined with a tangy, meaty edge that teases the palate. This balanced hybrid promises euphoric, mood-lifting highs, grade A bag appeal, and pronounced terpenes, flourishing equally well indoors, outdoors, and in greenhouses.

Growing from sprout to harvest in just 65–75 days, it matures into a bushy 20–28 in. specimen that rewards growers with 120–150 g/plant. At the start of Sour Stomper’s life, it grows squat and dense like an indica, but once flowering kicks in, it unveils its OG lineage with a remarkable stretch, becoming up to four times taller. This stretch can be harnessed through SCRoG or simple defoliation to maximize light exposure and airflow. Be prepared for a potent fragrance, as its high odor profile demands proactive ventilation.

Finished colas shimmer with a heavy dusting of crystal, releasing pine-lemon and grape-driven terpenes at every twist of the jar. Its buds are incredibly resinous, needing little to no trimming. The effect is uplifting and sociable, easing stress and brightening spirits while delivering a gentle body relaxation. Sour Stomper’s exceptional resin yield makes it an excellent candidate for concentrates and solventless extracts.

Flowering Time 65–70 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 120–150 g/plant

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Samsquanch OG Auto

Samsquanch OG Auto - Mephisto Genetics

Samsquanch OG Auto is a 60/40 indica-dominant strain, born from the legendary Yeti OG and 3 Bears OG. Bred to perfection by Mephisto, this F6 feminized auto exhibits a sturdy, cola-packed structure and exudes classic OG funk with notes of sour earth and skunk. It offers a blissful, couch-locking effect ideal for unwinding after a long day.

Reaching 28–35 in. tall over a 70–75-day cycle, it thrives in both indoor and outdoor setups, branching profusely into multiple bud sites. Growers should employ canopy maintenance—pruning lower foliage and applying LST—to channel energy towards the top colas. With medium odor intensity, a carbon filter will suffice to keep smells in check. Given proper care, this strain yields an impressive 100–150 g/plant of vibrant lime-hued buds.

Samsquanch OG’s finished product is well worth the wait: Its flowers are tight, dense nuggets blanketed in sticky resin, giving off a pungent, gassy aroma with earthy undertones. The flavor profile is savory and slightly spicy, finishing with a lingering diesel kick. High in therapeutic potential, it uplifts mood, sparks appetite, and offers deep relaxation without overwhelming sedation.

Flowering Time 70–75 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 100–150 g/plant

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Fugue State Auto

Fugue State Auto - Mephisto Genetics

Fugue State Auto, an illustrious 65/35 sativa-dominant strain, is a vigorous spawn of the sublime matrimony between Archive Seeds’ Amnesia Haze BX1 and Mephisto’s Walter White. This F4 autoflowering cultivar boasts a rapid 70–80-day cycle and exceptional resin production. Its open, airy branching structure showcases its Haze heritage while remaining easy to manage.

Indoor, outdoor, and greenhouse cultivation methods all suit Fugue State Auto. It flourishes between 28–39 in. tall and adapts brilliantly to SCROG, low-stress training, or light defoliation for optimum light penetration. Vigilance during late flower is key to prevent moisture buildup around thick colas, thereby avoiding potential mold issues. Its novice-friendly nature makes it accessible for growers seeking a fast-flowering sativa, with each plant producing 90–150 grams of connoisseur cannabis.

The buds are conical and resin-soaked, showing great bag appeal, while emitting bright citrus and spicy pepper notes with that classic Haze zing. Consumers describe a lively, uplifting high that sparks creativity and joy, ideal for daytime use. Rich in limonene and pinene, it also excels in solventless extractions and craft hash making. Not for novice smokers though!

Flowering Time 70–80 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 90–150 g/plant

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Fantasmo Express Auto

Fantasmo Express Auto - Mephisto Genetics

Fantasmo Express Auto is a 70/30 sativa-dominant F5 feminized autoflower, blending Rare Dankness’ OG Ghost Train Haze #1 with an auto WW1. This is Mephisto’s most sativa-dominant cultivar available. It bursts forth with lemony haze aromas and a subtle pine-earth undercurrent. The euphoric, energetic high is perfect for sparking social vibes and creative pursuits.

Starting small and squat, this strain quickly transforms during stretch, quadrupling in height over 3 feet and growing slender branches topped with long, stacked colas. Its quick 70–80-day cycle makes growing sativa cannabis accessible to anyone. The plant’s lanky branches and open bud sites lend themselves to greenhouse or indoor growth with minimal training. Despite its sativa lean, it remains a remarkably mold resistant strain thanks to its airy canopy.

Nugs form in delicate clusters, coated in glistening resin that captures bright citrus and spicy herbal terpenes. On the palate, expect juicy lemon zest with a tangy edge. The smoke is smooth, delivering a clean, uplifting buzz that can enhance mood and focus. Its moderate yields of 75–100 g/plant belie the potency hidden within each sticky bud, ideal for artisanal extracts.

Flowering Time 70–80 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 75–100 g/plant

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3 Bears OG Auto

3 Bears OG Auto - Mephisto Genetics

3 Bears OG Auto is a robust 70/30 indica-skewed F6 feminized automatic, marrying Karma’s Bear OG cut with a Triangle Kush F3, delivering top-tier OG quality cannabis. Its stout stature and dense branching yield compact, rock-hard buds laden with lemon-funk aromas. The effect is deeply calming, reducing stress and soothing chronic aches.

This strain wraps up its life cycle in 65–75 days, topping out at a manageable 20–31 in. Growers should tuck leaves around days 20–30 to boost secondary bud development and harness its impressive flower-to-leaf ratio. An ideal indoor strain, 3 Bears OG appreciates a Sea of Green setup for maximum yield potential, reaping 75–110 g/plant. The high odor output calls for decent ventilation or carbon filtration.

Flowers showcase a striking contrast of dark green and vibrant purple hues, all blanketed in a thick layer of crystalline trichomes. The flavor marries juicy watermelon sweetness with sour OG undertones, leaving a lingering gassy finish. With excellent resin yields, it’s a prime choice for hash and rosin aficionados.

Flowering Time 70–75 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 75–110 g/plant

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Alien Vs Triangle Auto

Alien Vs Triangle Auto - Mephisto Genetics

Alien vs. Triangle Auto, or AVT, is a powerhouse F2 feminized autoflower, combining Ripley’s OG and Triangle Kush genetics into a 40/60 indica-sativa hybrid. This weed is loaded with spicy-skunky aromas and a zesty piney edge that commands attention. Its forearm-sized colas and awe-inspiring amount of resin contribute to its skyrocketing demand. Users praise its balanced, potent high that uplifts yet anchors the body.

Maturing in just 75–85 days, it grows to a 3–4 foot stature, branching wide to accommodate dozens of resinous colas. It responds exceptionally well to SCROG, super-cropping, or LST to shape a multi-cola canopy. Structurally, AVT plants have an open formation, which serves as an advantage in warding off botyrtis mold and powdery mildew issues. Their resilience and adaptability make these seeds desirable for both indoor and outdoor cultivation methods. With a high odor profile, growers should plan for robust smell control.

With its incredible physical aesthetics and abundant resin production, AVT flaunts impressive bag appeal. Buds are resin-drenched, exhibiting a frosty sheen and dense, chunky structure. The flavor is a complex dance of earth, citrus, and spice, finishing with a lingering skew of gas. Testing above 25% THC, it delivers a long-lasting euphoria and powerful body buzz, making it a standout for craft connoisseurs.

Flowering Time 75–85 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 120–150 g/plant

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Grape Walker Kush Auto

Grape Walker Kush Auto - Mephisto Genetics

Grape Walker Kush Auto fuses Grape Crinkle with Skywalker in an F3 feminized automatic format, yielding a balanced 60/40 indica-to-sativa hybrid. This strain is prized for its dank OG backbone laced with deep grape overtones—a truly “grapey, kushy” experience that lives up to co-founder Tim’s endorsement: “What’s not to like?”

As a grower’s delight, Grape Walker Kush Auto reaches 60–90 cm over a 75–85-day cycle from sprout. She thrives under light leaf-tucking to unveil lower bud sites and benefits from gentle training to coax out multiple colas. Despite her high odor profile, she remains relatively stress-resilient; with proper care, yields of 90–120 g per plant are easily attainable, and denser plantings deliver a lush, resin-soaked canopy.

The finished flowers are a sight to behold: Dense, lime-tinged buds cloaked in sticky white frost. Aromas of earthy funk and pine give way on the exhale to sweet grape and kushy spice. THC levels average in the low twenties, offering a potent, balanced high that eases aches, stimulates appetite, and promotes deep rest. A rich terpene blend of myrcene, caryophyllene, and humulene ensures both extract aficionados and casual consumers will find plenty of resinous returns.

Flowering Time 75–85 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 90–120 g/plant

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Creme De La Chem Auto

Creme De La Chem Auto - Mephisto Genetics

Creme de la Chem Auto is a 70/30 indica-dominant F5 feminized autoflower, blending the pungent Chemdogging with the frosty Stardawg Illuminati cut. It greets growers with heavy notes of spice, floral incense, and diesel, backed by a rich, long-lasting high. This strain shines as both a recreational delight and a therapeutic workhorse, particularly for treating aches, pains and insomnia.

Creme de la Chem is a superb choice for indoor cultivation due to its compact size, growing between 22–31 inches tall with an equal stretch in width. Its bushy build benefits from leaf-tucking for deep light penetration and pruning of thinner, lower branches for superior secondary cola formation. A fast-flowering strain, its cycle completes in 65 to 70 days, offering yields of 90–120 g/plant. Despite its explosive aromas, novice cultivators find it exceptionally straightforward to manage.

The plant showcases an appealing contrast between a thick white resin coat and an array of vibrant colors. Buds emerge as dense, golf-ball-sized nuggets sheathed in a thick, almost furry coat of trichomes. The palate is treated to a spicy, fuel-driven symphony with earthy undertones and a smooth finish. Loaded with resin and terpenes, it’s ideal for high-grade extracts and all manner of concentrates.

Flowering Time 65–70 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 90–120 g/plant

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Skywalker Auto

Skywalker Auto - Mephisto Genetics

Skywalker Auto is a 70/30 indica-dominant F7 feminized autoflower, crafted from a prized Skywalker Kush cut and Triangle Kush genetics. This popular Mephisto variety is known for its high quality from scent to sensation, projecting a pungent, piney OG aroma with a hint of lemon brightness. The effect is profoundly sedative, delivering a heavy body stone paired with cerebral bliss.

This medium-height plant grows between 24–35 inches and features an open structure that allows ample light for optimal bud development. Leaf tucking is recommended to further stimulate upward branch growth. While Skywalker Auto is well-suited for outdoor and greenhouse cultivation, indoor growers should incorporate efficient air filtration systems to counteract its potent aroma. Despite not boasting large-size buds, Skywalker Auto compensates with dense, resin-coated colas.

Growers should plan for significant odor and consider double-bagging cured buds for transport. The finished flowers are chunky and rock-hard, cloaked in milky trichomes and vivid orange pistils. On the palate, earthy and sour notes meld with sweet citrus layers. Its high myrcene content underpins the swift and potent stone of Skywalker Auto, affecting both the mind and body with powerful couch-lock effects.

Flowering Time 70 days from seed
Brand Mephisto Genetics
Pack Size 3 seeds
Yield 80–100 g/plant

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About Mephisto Genetics

Mephisto Genetics Logo

Mephisto Genetics, a behemoth in the world of autoflower cannabis seed breeding, has been revolutionizing perceptions of what autoflower seed genetics can achieve. Guided by the joint efforts of best friends Mitch and Tim along with a compact yet passionate team, Mephisto has elevated autoflowers from their historically lackluster reputation of low-yield, minimal aroma, and muted effects.

Through their skillful cross-breeding with photoperiod seeds and subsequent back-crossing into feminized autoflower seeds, Mephisto Genetics has created top-tier autoflower strains that refuse to compromise on yield or potency. Their secret weapon is an extensive seed library, amassed by the auto-obsessed Mitch and Tim. This impressive collection results in one-of-a-kind strains born from unique and rare seeds stretching back decades.

Starting as a light-hearted challenge between Mitch and Tim to innovate consistently exceptional autoflower strains in 2007, Mephisto Genetics has come a long way. Their journey saw them establishing a farm located in the mountainous Spanish countryside in 2012. Later on in 2017, they set up a US distribution hub to cater to their biggest customer base. They upgraded to a larger facility in Spain in 2020, albeit with operations halted due to Covid-19 travel restrictions.

Now back at full speed, they’ve resumed production for existing strains, with a slew of new ones nearing release. Mephisto upholds its renown as a premium feminized autoflower seed breeder by adhering strictly to trademark standards of quality.

Awards and accolades have followed suit, with Mephisto claiming the revered Best Breeder title at the 2023 Autoflower World Cup and the recent Spannabis fair, Europe’s largest cannabis expo. Closer home, they also scooped up the Best Breeder recognition at the 2023 American Autoflower Cup held in Los Angeles, CA.

This Double Grape is so dang close. Hopefully this'll be the last feeding.
byu/ReverendHambone inMephHeads

But these awards are second-hand joy for Mitch and Tim, who find greatest pride in their well-rounded body of breeding work and the organic global community of fans and growers supporting them.

Hailing from a spanking new hub in Barcelona, Spain, Mephisto Genetics strains are carefully developed, tested, and stabilized over nearly two years. Once the team confers approval on particularly stellar strain traits, commercial runs of seeds are conducted with a reputable producer in either the US or Canada—markets with significant traction for this powerful breed.

In the US, the highly anticipated release of these new feminized autoflower seeds takes place bi-weekly on the Mephisto website, stirring excitement among the growing autoflowering community. Rewarding these loyal brand fans, Mephisto has launched the “Piggy Points” program. Additionally, respectably recognized seedbanks like Seedsman keep a steady supply of Mephisto’s feminized autoflower seeds.

Fugue state timber at day 93. Grown in autopot/coco. What a beaaaaast.
byu/Slapyobro inMephHeads

Currently, distribution centers and grow hubs sprawl across multiple countries and continents, ensuring the swift delivery of seeds. In fact, the vast majority of all Mephisto seed sales take place in the US, which stands testament to both the popularity of autoflowers and the indomitable brand reputation in America.

Mephisto Genetics shows no signs of slowing down, with numerous strain projects slated for resumption that will hit their website upon final rounds of testing and runtime completion. Among these highly anticipated releases, expect unique Gelato crosses featuring different dessert strain phenotypes, legendary genetics including a 30+ year-old cut of old school haze for lovers of robust sativa effects, and more CBD-rich strains as Mephisto continues its exploration with this intriguing cannabinoid. No doubt, exciting times lie ahead for seed collectors and growers!

Jared Cox profile image

Jared Cox is the author behind Mold Resistant Strains. He is a cannabis grower, breeder, and archivist of seeds. His work across several disciplines extensively covers cannabis genetics, cultivation, processing, and sales.

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