20 Best Low-THC Cannabis Strains to Grow: Seed Guide

Top Best Low-THC Cannabis Strains Seed Buyers' Guide

View 20 of the best low-THC cannabis strains perfect for cultivating—featuring reduced THC levels that are manageably mild. These strains provide a gentler experience, ideal for users seeking the therapeutic benefits of cannabis without an overwhelming, psychoactive high. If chill and mellow genetics are what you’re after, you’re in the right spot. Every low-THC strain listed below is available as feminized seeds in photoperiod or autoflowering, with fast and discreet shipping across the USA.


CBDV 1:1 Auto

CBDV 1:1 Auto by Seedsman

Seedsman’s CBDV:CBD 1:1 Auto is a groundbreaking medical cannabis cultivar, boasting an exceptional balance of CBDV and CBD while maintaining minimal THC levels below 0.3%. This sativa-dominant hybrid is the product of innovative breeding, yielding a plant rich in medicinal potential. The autoflowering plants flourish in both indoor and outdoor settings, with a swift 9–10 week turnaround indoors, and the capacity for multiple outdoor harvests in a year due to its brief life-cycle. Aromatically, the buds exude a fresh, balsamic scent, reminiscent of pine trees and resin. CBDV:CBD 1:1 Auto offers a profoundly calming and soothing experience, perfect for medical cannabis users seeking relief without the psychoactive high.

Flowering Time 9–10 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 350–450 g/m2
THC <0.3%

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CBG Limonene Hemp

CBG Limonene Hemp by Trilogene Seeds

CBG Limonene Hemp, a product of Trilogene Seeds, is a predominantly indica high-CBG strain resulting from a cross of CBGambit and CBG Clone S1. With a remarkably high CBG:THC ratio of about 60:1 and minimal THC content of 0.25%, it contains a great deal of therapeutic potential without inducing psychoactive effects. This strong, wind-resistant strain boasts broad fan leaves and compact, light green buds sprinkled with trichomes, making its aesthetic appeal as robust as its resilience. It’s best suited for outdoor cultivation, flowering within 75 to 85 days and yielding a generous harvest. With an invigorating citrus flavor profile and effects reported to promote clarity and uplift, CBG Limonene Hemp offers a refreshing, non-intoxicating experience.

Flowering Time 10–12 weeks
Brand Trilogene Seeds
Pack Size 5 seeds
Yield 450–1150 g/plant
THC 0.25%

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CBD Crack 1:1 Auto

CBD Crack 1:1 Auto by Fast Buds

CBD Crack Auto 1:1 is a balanced THC/CBD autoflowering strain with medicinal benefits and an excellent choice for novice and moderate consumers. The weed features a blend of peppery, floral, and fresh fruity terpenes that leave behind a taste of freshly cut mangoes. The strain grows up to 39 inches, providing enjoyable effects for consumers with low tolerances. Its cannabinoid profile provides therapeutic benefits like pain relief, cramp alleviation, and anxiety reduction without overwhelming psychoactive sensations. The plant yields large, sweet, and dense mango-flavored buds that are conveniently compact and ideal for homegrown medicine, boasting an equal concentration of 7% THC and 7% CBD.

Flowering Time 9–10 weeks from seed
Brand Fast Buds
Pack Size 1/3/5/10 seeds
Yield 450–550 g/m2
THC 7%

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CBD Charlotte’s Angel

CBD Charlotte's Angel by Dutch Passion

CBD Charlotte’s Angel, a high-CBD strain from Dutch Passion, is made from the high-CBD Dutch Charlotte and the Amsterdam exclusive Red Angel CBD strains. The plants are sativa-dominant and require 9 to 12 weeks of flowering, promising substantial yields. Its herbal buds have tones of pine and diesel, with incredible resin production ideal for high-CBD, low-THC concentrates. With negligible THC levels averaging at 0.7% maximum and CBD levels around 15%, CBD Charlotte’s Angel provides a safe therapeutic option for patients who wish to avoid getting high. Its calming effect supports relaxation, well-being, and has anti-anxiety properties.

Flowering Time 9–12 weeks
Brand Dutch Passion
Pack Size 1/3/5/10 seeds
Yield 400–500 g/m2
THC 0.7%

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Pink Kush CBD 30:1 Auto

Pink Kush CBD 30:1 Auto by Seedsman

Pink Kush CBD 30:1 Auto is a premium low-THC Kush strain bred from Pink Kush CBD Auto and Pink Afghan CBD Auto strains. This 90% indica autoflowering plant, which features an appealing pink hue on its buds, is suitable for nearly all growing environments and matures swiftly within just nine weeks. Besides its rapid growth, the ability to harvest multiple times in a year under warm climate conditions contributes to its appeal among growers. Pink Kush CBD Auto offers an earthy profile with fruit, pine, and damp forest notes. Its remarkable CBD:THC ratio of at least 30:1, boasts approx. 17% CBD and a minimal 0.5% THC, culminating in a gentle, relaxing body effect.

Flowering Time 9 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield Good
THC 0.5%

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Peyote Wi-Fi CBD 2:1

Peyote Wi-Fi CBD 2:1 by Seedsman

Peyote Wi-Fi CBD 2:1, hailing from a lineage including Peyote Purple, WiFi OG, and CBD-rich Candida phenotype Seedsman CBD #2, is a therapeutic cannabis strain specially bred for medical consumers. A result of strategically selected genetics, it delivers a calming experience with twice as much CBD as THC, moderating its psychoactive effects. With an indoor flowering period of 65 days, and an outdoor harvest around mid-October, Peyote Wi-Fi CBD 2:1 is adaptable to various environments, showcasing resilience and ease of cultivation. Boasting 12–14% CBD and around 6–8% THC content, it imparts relief to various conditions without an overwhelming high.

Flowering Time 8–10 weeks
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 450–600 g/m2
THC 6–8%

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Glu CBD Auto

Glu CBD Auto by Trilogene Seeds

Glu CBD Auto is a robust, CBD-dominant hybrid perfect for enthusiasts preferring low-THC strains and high CBD to THC ratios, reaching up to 30:1. The result of crossbreeding Alpha Auto and Purple Thai, this purple weed strain showcases deep, dark purple buds against dark green leaves, growing into short and stout plants that eliminate the need for trellising. Glu CBD Auto feminized seeds are ideal for indoor cultivation or warmer climatic regions, thanks to the strain’s mold resistance. Its high-density buds feature sweet, earthy flavors with the elegance of a Californian Redwood tree scent. The calming effect provides stress and anxiety relief without getting you high, attributing to its minimal THC of 0.46%.

Flowering Time 80 days from seed
Brand Trilogene Seeds
Pack Size 5 seeds
Yield 85–170 g/plant
THC 0.24%

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Blueberry CBD

Blueberry CBD by ILGM

Blueberry is a legendary indica-dominant weed strain best known for its fruity aroma and flavor akin to fresh blueberries. This high-CBD version marries the tantalizing terpenes with up to 16% CBD content and less than 1% THC, ensuring a mellow experience without the psychoactive high. Originating from a rich lineage involving Afghani indica, Purple Thai sativa, and Thai sativa, these feminized seeds give rise to robust, expansive plants. They flourish in most climates, requiring ample space for their tall and wide stature, particularly when grown indoors. Blueberry CBD is a top choice for those seeking relief and tranquility, offering a soothing journey enveloped in a burst of berry goodness.

Flowering Time 9 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 18–25 oz/plant
THC <1%

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Red Pure CBD Auto

Red Pure CBD Auto by Sweet Seeds

Red Pure CBD Auto, a predominantly indica strain, is highly therapeutic with its generous CBD content which sits at 15–17%. Bred from Sweet Pure CBD and Red Poison Auto, this low-THC strain, with THC levels peaking at a mere 0.4–0.5%, ensures no psychoactive effects are experienced. Finished in just nine weeks, these plants grow in a typical indica structure with strong central stems, offering indoor yields of up to 500 g/m2 and outdoor harvests of 30–100 g/plant. Red Pure CBD Auto stands out visually with nearly all plants boasting striking red-hued buds. Its flavor and aroma profile incorporates a blend of sweet earthiness with hints of pine, cypress, and berries. Ideal for medicinal users seeking cannabis benefits without the high, this strain promises total relaxation.

Flowering Time 9 weeks from seed
Brand Sweet Seeds
Pack Size 3/5 seeds
Yield 450–500 g/m2
THC 0.4–0.5%

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CBD Skunk Haze

CBD Skunk Haze by Dutch Passion

CBD Skunk Haze packs a rich blend of CBD and THC, boasting a balanced 1:1 ratio that averages 7.5% for both. This strain results from a collaboration between Dutch Passion and CBD Crew, aiming to cater to both medical and recreational users seeking a milder yet satisfying experience. The plants are perform best in controlled greenhouses or indoors, producing large, resinous flowers that exude a spicy cedar aroma with citrus and pine notes. The effects of CBD Skunk Haze are calm and clear-headed, providing a stress-free and functional high without the debilitating stone of some higher THC strains.

Flowering Time 9–10 weeks
Brand Dutch Passion
Pack Size 1/3/5/10 seeds
Yield 400–500 g/m2
THC 7.5%

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CBG Relief Auto

CBG Relief Auto by Seedsman

Seedsman’s CBG Relief Auto introduces the cannabis community to the novel properties of cannabigerol (CBG), a cannabinoid that has garnered considerable attention for its potential benefits. As an autoflowering strain, it provides a straightforward cultivation experience, transitioning from germination to bloom in a mere 8 to 10 weeks. The plant adopts a compact, Christmas tree-like structure, boasting strong branches and a decent yield ranging from 350–450 g/m2. Interestingly, this strain produces an abundance of CBG while maintaining negligible levels of THC and CBD, rendering it a legal option in many jurisdictions. Its floral terpene profile further places CBG Relief Auto as a unique and intriguing addition to any cannabis garden.

Flowering Time 8–10 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 350–450 g/m2
THC <1%

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CBD #1

CBD #1 by Ace Seeds

CBD #1 is Ace Seeds’ low-THC, high-CBD feminized cannabis strain, boasting a CBD:THC ratio of roughly 20:1, achieved through three years of dedicated breeding. This strain is a cross of the CBD-rich Cannatonic S1 and Afghan ErdPurt, yielding buds with 13–17% CBD and just 0.6–0.7% THC—void of any psychotropic high. The 60% sativa-dominant plants are resilient, thriving in various conditions and producing dense, resinous buds perfect for CBD-rich extracts. The aroma is a complex mix of tropical fruit and tangerine from Cannatonic, enriched by sweet, floral undertones from ErdPurt. Recommended for therapeutic use, CBD #1 provides relief from pain, stress, anxiety, and paranoia, making it a top choice for medicinal consumers.

Flowering Time 7–8 weeks
Brand Ace Seeds
Pack Size 3/5 seeds
Yield Medium/High
THC 0.6–0.7%

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Honey Peach CBD Auto

Honey Peach CBD Auto by Sweet Seeds

Honey Peach CBD Auto, an award-winning strain from Sweet Seeds, is a 5th generation autoflower strain that’s designed to offer a super-fast growth cycle and hefty CBD content with moderately low levels of THC. This 70% indica strain grows with a robust central stem and multiple side-branches, reaching a height of 23–39 inches and offering generous indoor and outdoor yields. Noted for its incredible flavor profile, Honey Peach CBD Auto weed exudes a mix of sweet and fruity notes, with hints of peach, lemon, and wood. With 7–12% CBD and 6–9% THC levels, the effect is medicinal and relaxing. Its terpene-rich nature and plentiful resin make it ideal for extract production.

Flowering Time 8 weeks from seed
Brand Sweet Seeds
Pack Size 3/5 seeds
Yield 400–550 g/m2
THC 6–9%

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White Widow CBD

White Widow CBD by ILGM

White Widow CBD, a feminized indica-dominant strain, finds its roots in the legendary Amsterdam cannabis scene, blending South Indian indica and South American sativa genetics. Easy to grow and resilient, it thrives in both indoor and outdoor settings, reaching a manageable height of 30–43 inches. With 1:1 balanced 6–9% CBD and THC levels, it offers a gentle, uplifting experience, aiding creativity without overwhelming. The buds, covered in white resin, emit an earthy, spicy aroma, leaving a sweet, pine-tinged aftertaste upon consumption. This makes White Widow CBD a favorite for both novice cultivators and consumers seeking a mellow, therapeutic strain.

Flowering Time 8–9 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 10 oz/plant
THC 6–9%

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Purple Star CBD Auto

Purple Star CBD Auto by Atlas Seed

Purple Star CBD Auto is an 80% indica strain, notable for its stunning purple coloration and a CBD to THC ratio averaging at 27:1. This strain, a blend of Grape Ape CBD Auto and Wilhelmina CBD Auto, offers good mold resistance and a beginner-friendly cultivation level. The plants typically reach a height of 31–35 inches, promising bountiful yields in both indoor and outdoor settings within a swift 70-day cycle from seed to harvest. THC levels are exceptionally low at 0.3%, while CBD content ranges between 9–13%, assuring a mild and soothing experience. The weed is dominated by sweet grape jam and berries, paired with a fruity aroma, serving as a delightful choice for those seeking relaxation without the high.

Flowering Time 70 days from seed
Brand Atlas Seed
Pack Size 5 + 2 seeds
Yield 55–110 g/plant
THC 0.3%

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Doctor Seedsman CBD 30:1

Doctor Seedsman CBD 30:1 by Seedsman

Doctor Seedsman CBD, boasting an extraordinary CBD:THC ratio of 30:1, stands out as a pinnacle of breeding excellence, achieving high levels of CBD while maintaining less than 1% THC. This 80% sativa strain, derived from a high-CBD cultivar known as CBD Asia, exhibits robust growth patterns, remaining relatively short and squat throughout its growth cycle. Indoor flowering spans 8 to 9 weeks, with outdoor harvests ready in early October for those in northern climates. The buds produced are dense, resin-covered, and yield generously. Doctor Seedsman CBD provides a potent aroma and a strong taste, featuring pine and ginger notes, with a deeply relaxing, non-psychoactive effect on the body, thanks to its 20% CBD content and sub-1% THC levels.

Flowering Time 8–9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 450–600 g/m2
THC <1%

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CBD 20:1 Auto

CBD 20:1 Auto by Fast Buds

CBD Auto 20:1 is Fast Buds’ premier medicinal cannabis strain, boasting a remarkable CBD concentration of 20%, while maintaining a minimal THC level at 0.3%. This cannabinoid profile renders it legal in numerous countries, providing a viable option for those seeking relief without the pronounced psychoactive effects typical of higher THC weed. This strain’s medicinal nature lends itself to products such as CBD edibles, oils, and creams. Growing CBD Auto 20:1 seeds is easy, with short plants reaching a height of three feet and yielding approximately 500 g/m2 within a swift 70-day flowering period. With its firm buds brimming with therapeutic properties and a gentle, sweet flavor profile highlighted by fruity and honeyed notes, CBD Auto 20:1 offers a delightful and effective medicinal experience.

Flowering Time 9–10 weeks
Brand Fast Buds
Pack Size 1/3/5/10 seeds
Yield 350–450 g/m2
THC 0.3–0.85%

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Harlequin

Harlequin by ILGM

Harlequin, a reputable medical cannabis strain, boasts high CBD levels of 10–15% with up to 7% THC content, making it a favorite for both medicinal relief and recreational enjoyment. This sativa-dominant strain thrives in controlled climates, whether grown in soil or hydroponically, yielding abundantly in 8 to 9 weeks indoors or in early fall outdoors. Harlequin delivers an uplifting and energizing buzz, perfectly balancing sativa and indica effects, and is particularly popular for its ability to alleviate pain without intense psychoactive effects. The aroma blends earthiness with tropical mango, while the flavor profile is a spicy, herbal delight.

Flowering Time 8–9 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 14–17 oz/plant
THC Up to 7%

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CBD Haze Auto

CBD Haze Auto by Homegrown

CBD Haze Autoflower seamlessly blends the uplifting qualities of Haze genetics with the therapeutic benefits of CBD, resulting in a strain with a gentle and soothing effect. This robust hybrid, a cross between a pure line CBD Auto and Haze XXL Auto, offers a sweet and complex terpene profile, combining notes of incense, citrus, and pine. With its nearly balanced 7% THC and 8% CBD levels, it provides a clear-headed and chill experience, ideal for socializing or focused activities. This strain flourishes in a variety of settings and completes its harvest in a swift ten-week growth cycle. Compact and bushy, with striking orange pistils and resinous buds, CBD Haze Autoflower stands out as a top choice for those seeking low-THC options without sacrificing quality or experience.

Flowering Time 10–12 weeks from seed
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield High
THC 6–8%

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Lucky Lucy CBD

Lucky Lucy CBD by Trilogene Seeds

Lucky Lucy CBD is a sativa-leaning hybrid noted for its medical properties and easy cultivation, boasting a potential CBD:THC ratio of 32:1. Developed by Trilogene Seeds, it combines Sweet Grass and Sweet Wife genetics, thriving in diverse outdoor conditions with sturdy growth and wind resistance. The strain features dense buds with a unique flavor profile of dank cheese and a complex aroma of cheese, hibiscus tea, and blue cheese. With a mere 0.5% THC and a substantial 15.9% CBD, Lucky Lucy CBD offers a non-psychoactive experience, providing relief from anxiety, stress, and chronic pain while maintaining mental clarity and focus. Its ease of growth and significant therapeutic benefits make it a great pick for both novice gardeners and medical users alike.

Flowering Time 8–10 weeks
Brand Trilogene Seeds
Pack Size 5 seeds
Yield 450–2250 g/plant
THC 0.5%

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Jared Cox profile image

Jared Cox is the author behind Mold Resistant Strains. He is a cannabis grower, breeder, and archivist of seeds. His work across several disciplines extensively covers cannabis genetics, cultivation, processing, and sales.

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