20 Best High-CBD Strains of Medical Cannabis: Seed Guide

Top 20 Best High-CBD Medical Marijuana Strains

Best CBD strains with the most CBD content. Grow the best high-CBD strains of medical marijuana or CBD hemp. High-CBD seeds for sale as feminized or autoflower with guaranteed US shipping.

Cannabidiol (CBD) is a cannabinoid that is used as a natural remedy for many ailments. CBD does not cause a high by itself. Certain varieties of cannabis known as CBD strains produce large amounts of CBD.

High-CBD cannabis seeds allow you to grow your own medicinal CBD strains at home or commercially.

Every CBD strain listed below is selected for high-CBD content—ordered per section by CBD strains with the highest CBD:THC ratio. Some are non-psychoactive CBD hemp with little to no THC, while others are psychoactive and contain more.


Best Feminized High-CBD Strains

Doctor Seedsman CBD 30:1

Doctor Seedsman CBD 30:1 feminized seeds medical cannabis Seedsman

Doctor Seedsman CBD 30:1 is a high-CBD cannabis strain, resulting from an extensive search for a variety with increased CBD levels and less than 1% THC. The seeds of Doctor Seedsman CBD 30:1 grow into short, sturdy plants that yield dense, resinous buds without psychoactive effects. This strain features strong pine and ginger aromas and flavors. Its effects are predominantly body-relaxing.

Flowering Time 8–9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield High
CBD 20%
THC Less than 1%

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CBD Ratio 30:1

CBD Ratio 30:1 medical marijuana strain seeds

CBD Ratio 30:1 is a predominantly indica CBD strain that provides therapeutic and soothing effects without inducing a high. These buds have a strong pine or wood aroma and taste, thanks to the presence of the alpha-pinene terpene. The plants have a compact, bushy growth pattern, making them suitable for cultivation in limited spaces. The flowers of CBD Ratio 30:1 are dense and coated in resin.

Flowering Time 8–9 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 500 g/m2
CBD 24–30%
THC 1%

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CBD Fire Kush 30:1

CBD Fire Kush 30:1 Medicinal Marijuana Strain Fem Seeds

CBD Fire Kush 30:1 is primarily an indica hybrid, resulting from the crossbreeding of Fire Kush and Candyland CBD. It’s an easy-to-grow CBD strain suitable for both novice and experienced growers. This strain grows rapidly, progressing from seed to harvest swiftly for photoperiod varieties. The buds of CBD Fire Kush 30:1 possess a potent indica character with herbal, earthy, and fruity notes. With THC levels averaging a mere 0.1–0.2%, CBD Fire Kush 30:1 is entirely non-psychoactive and can be classified as CBD hemp.

Flowering Time 7 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 450–600 g/m2
CBD 8–10%
THC 0.1–0.2%

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Charlotte’s Angel CBD

Charlotte's Angel CBD weed strain medical seeds

Charlotte’s Angel CBD, a well-regarded medical cannabis strain, features high CBD and low THC levels, accompanied by abundant resin. Although its growth period extends a few weeks longer than typical CBD strains, this delay is rewarded with generous yields. The strain’s buds emit a herbal or piney scent and taste, offering calming effects without inducing psychoactivity.

Flowering Time 9–12 weeks
Brand Dutch Passion
Pack Size 1/3/5/10 seeds
Yield High
CBD 15%
THC 0.7%

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Carma CBD

Carma CBD medical weed marijuana seeds

Carma CBD, predominantly an indica strain, is derived from Italian industrial hemp. It yields cannabis flowers with a sweet aroma, high CBD content, and minimal THC levels. Known for their resilience, Carma CBD plants are relatively easy to cultivate, though they grow tall. Importantly, Carma CBD does not induce psychedelic effects.

Flowering Time 7 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 14–17 oz/plant
CBD 6–9%
THC 0.3%

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CBD ACDC

CBD ACDC Fem Seeds Medical Cannabis

CBD ACDC is a high-yielding hybrid created by crossing two top-selling medical marijuana strains: ACDC and CBD OG Kush. This strain produces flowers with robust resin output and high CBD concentrations. CBD ACDC cannabis delivers therapeutic, non-intoxicating effects.

Flowering Time 10–11 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 23 oz/m2
CBD 18%
THC 1%

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CBD Harlequin 18:1

CBD Harlequin 18:1 medical high-CBD seeds strain

CBD Harlequin 18:1 is a high-CBD strain with a diverse lineage, perfect for medicinal use while maintaining clarity. This strain features dense indica buds, high in CBD and low in THC. CBD Harlequin 18:1 cannabis offers fruity citrus flavors and an impressive terpene profile.

Flowering Time 8–9 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 400–500 g/m2
CBD 12–14%
THC 3–6%

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OG Kush CBD

OG Kush CBD Strain Seeds

OG Kush CBD, a high-CBD variant of the renowned American strain OG Kush, boasts a potent aroma. This strain delivers a sense of comfort and relaxation without causing a high. The seeds of OG Kush CBD develop into short, compact plants that yield abundant, top-quality CBD-rich buds, containing minimal THC levels.

Flowering Time 8 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 16–17 oz/3×3 ft
CBD 15%
THC Less than 1%

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CBD White Widow 10:1

CBD White Widow 10:1 medical high-CBD cannabis seeds

CBD White Widow 10:1, an enhanced CBD variant of the globally acclaimed White Widow cannabis strain, boasts exceptionally frost-covered flowers rich in trichomes. These buds offer medicinal benefits with minimal to no psychoactive impact. The seeds of CBD White Widow 10:1 develop into sturdy, easy-to-care-for plants that produce abundant yields. This strain retains the distinct aroma and flavor of the original White Widow.

Flowering Time 7–8 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 16–18 oz/m2
CBD 10%
THC 1%

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Mamba Negra CBD

Mamba Negra CBD weed strain feminized seeds

Mamba Negra CBD is a strain featuring high CBD and low THC levels, characterized by unusually large and dense buds. These seeds are ideal for cultivators aiming for abundant harvests of rich CBD flowers. The plants are versatile, thriving in various growing conditions, and yield impressive returns.

Flowering Time 9–10 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 500 g/m2
CBD 10–20%
THC 1–2%

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Peyote Wi-Fi CBD 2:1

Peyote Wi-Fi CBD 2:1 Medical Marijuana Strain Seeds

Peyote Wi-Fi CBD 2:1, an indica-sativa hybrid, yields twice as much CBD as THC. This strain results from crossbreeding Peyote Purple and Wi-Fi OG with the high-CBD variant, Candida, also known as Seedsman CBD #2. Peyote Wi-Fi CBD 2:1 cannabis provides medical users relief without causing debilitating effects.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield Undocumented
CBD 12–14%
THC 6–8%

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CBD Girl Scout Cookies 1:1

CBD Girl Scout Cookies 1:1 medical CBD seeds

CBD Girl Scout Cookies 1:1 is an evenly balanced medical marijuana strain with equal parts CBD and THC, derived from the highly acclaimed Girl Scout Cookies variety. This exotic hybrid yields a significant amount of top-quality psychoactive flowers, boasting exceptional terpene profiles. CBD Girl Scout Cookies 1:1 delivers potent effects, offering full-body relaxation and cerebral euphoria.

Flowering Time 8–10 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 400–500 g/m2
CBD 15%
THC 15%

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Cream & Cheese CBD 1:1

Cream & Cheese CBD 1:1 Medical Cannabis Feminized CBD Seeds

Cream & Cheese CBD 1:1 is a powerful CBD strain embodying the characteristics of a classic Cheese variety. It boasts a distinct Cheese aroma and flavor. The buds of Cream & Cheese CBD 1:1 are rich in both CBD and THC. Both medical and recreational cannabis users will appreciate the strain’s soothing body effects.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 400–600 g/m2
CBD 18%
THC 22%

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Best Autoflower High-CBD Strains

Red Pure CBD Auto

Red Pure CBD Autoflowering Medical Marijuana Seeds

Red Pure CBD Auto, developed by Sweet Seeds, is a rapid-growing, CBD-rich autoflowering strain. It reaches harvest in just nine weeks from germination. Around 95% of the plants produce striking red buds. This strain boasts a low THC level and high CBD content. It features a sweet, earthy aroma and flavor, complemented by notes of pine and berry. Red Pure CBD Auto lacks psychoactive effects.

Flowering Time 9 weeks
Brand Sweet Seeds
Pack Size 3/5 seeds
Yield 450–500 g/m2
CBD 15–17%
THC 0.4–0.5%

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Pink Kush CBD Auto 30:1

Pink Kush CBD Auto 30:1 medicinal strain weed seeds

Pink Kush CBD Auto 30:1 is a fast-maturing CBD strain featuring buds with a captivating pink hue. This indica-dominant autoflower becomes ready for harvest approximately 63 days after germination. It offers a mild body sensation without any psychoactive effects.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield High
CBD 17%
THC 0.5%

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Auto CBD Purple 20:1

Auto CBD Purple 20:1 Fem Seeds Medical Strain

Auto CBD Purple 20:1, a purple strain cross between Purple Kush CBD Auto and Purple Afghan CBD Auto, yields colorful buds with a fruity flavor. High in CBD and low in THC, this autoflowering medical marijuana strain is perfect for indica enthusiasts seeking a rapid harvest.

Flowering Time 8 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield Medium
CBD 17–19%
THC 0.2–0.5%

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Charlotte’s Angel CBD Auto

Charlotte's Angel CBD Auto Weed Seeds Medicinal Strain

Charlotte’s Angel CBD Auto, a new autoflowering variant of Dutch Passion’s high-CBD, low-THC strain, Charlotte’s Angel, offers the medicinal advantages of CBD. This strain provides a sense of well-being and relief without inducing a high. The plants of Charlotte’s Angel CBD Auto typically require about 70 days from germination to harvest, yielding abundant crops.

Flowering Time 10 weeks
Brand Dutch Passion
Pack Size 1/3/7 seeds
Yield High
CBD 16%
THC 0.7%

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CBD Cheese Auto

CBD Cheese Auto Strain High-CBD Seeds

CBD Cheese Auto is a pungent autoflower CBD strain with mild psychoactive effects. This variety of cannabis is a suitable choice for users with a low tolerance. CBD Cheese Auto seeds grow tall plants with large buds exuding a cheesy yet sweet fragrance.

Flowering Time 9 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 16–18 oz/m2
CBD 15%
THC 6%

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Critical Mass CBD Auto

Critical Mass CBD Auto medical cannabis strain seeds

Critical Mass CBD Auto is a CBD-rich autoflower version of the high-yielding marijuana strain Critical Mass. Its buds promote body relaxation and positive feelings without the couchlock effect. Critical Mass CBD Auto seeds are easy to grow and produce plants with critically large and heavy flowers. The aromas and flavors of Critical Mass CBD Auto are pungent and earthy.

Flowering Time 10–14 weeks from seed
Brand ILGM
Pack Size 5/10/20 seeds
Yield 5–15 oz/3×3 ft
CBD 6–9%
THC 6–9%

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Purple Kush CBD Auto 1:1

Purple Kush CBD Auto 1:1 Ratio Medical Strain Seeds

Purple Kush CBD Auto 1:1 is a mostly indica autoflowering hybrid of Purple Kush CBD Auto and Purple Afghan CBD Auto. This CBD strain is essentially the same plant Pink Kush CBD 30:1, but with a CBD:THC ratio of 1:1. The buds of Purple Kush CBD Auto 1:1 have an earthy and fruity taste and deliver a physical effect with no paranoia or anxiety.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield High
CBD 8%
THC 7%

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Read Next: Best Exotic Hybrid Strains of Marijuana

 

Disclaimer: Any medical information on this site is provided as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. We do not promote or undertake in illegal activities.

Jared Cox profile image

Jared Cox is the author behind Mold Resistant Strains. He is a cannabis grower, breeder, and archivist of seeds. His work across several disciplines extensively covers cannabis genetics, cultivation, processing, and sales.

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