20 Best American Strains of Marijuana to Grow 2022

20 Best American Weed Strains List Top

Award-winning US genetics—Best American marijuana strains of all time! Grow the best US weed strains. American marijuana seeds for sale with quick domestic delivery.

The best American strains of cannabis are highly in-demand. Marijuana breeders in the US have earned a reputation for producing sought-after weed strains with incredible strength and supreme quality.

You can grow American genetics as a beginner or professional by buying US marijuana seeds online.

Every American strain listed below is ready to purchase in feminized or autoflower seeds.

Best Feminized American Strains

OG Kush

OG Kush American weed strain

Overview: OG Kush is the single most popular American weed strain of all time. This exceptionally potent and flavorful marijuana from the US has championed cannabis markets since the nineties. OG Kush plants are notoriously difficult to grow, but ultimately worth the effort to many indoor and outdoor growers. The signature buds of OG Kush are big, chunky, and covered in trichomes. It has a sour woody fragrance. With THC content up to 26%, OG Kush delivers powerful and fast-acting narcotic effects.

Flowering Time 8–10 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 16–18 oz/m2

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Runtz

Runtz marijuana US strain seeds

Overview: Runtz is an award-winning American marijuana strain named for its colorful buds that smell and taste like a box of candy. A hybrid cross of Zkittlez and Gelato, Runtz plants produce exotic weed with great strength and resin content. Its high is mainly euphoric and uplifting. Runtz feminized seeds require the hands of experienced growers to perform at their best. The plants prefer a semi-humid climate to thrive and yet only yield averagely. 19–22% THC.

Flowering Time 9 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 400–450 g/m2

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Wedding Cake

Wedding Cake strain USA fem seeds

Overview: Wedding Cake is a potent indica strain hybrid from the US with an aroma of sweet vanilla cake, which led to its naming. The effects of Wedding Cake balance between cerebral euphoria and physical comfort. Wedding Cake marijuana plants yield bumper crops and are easy to grow regardless of skill level. The end product is dense and caked in resin with pink or purple highlights. Up to 25% THC.

Flowering Time 9–10 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 18–21 oz/3x3ft

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Blue Dream

Blue Dream weed strain West Coast USA

Overview: Blue Dream is a remarkable sativa strain hybrid from Humboldt County that’s loved equally by commercial growers and enthusiasts. Blue Dream plants grow very big and produce monster yields. Its buds are large and full of crystals with a sweet smell like blueberries. The effects of Blue Dream are uplifting and mentally stimulating. Up to 20% THC.

Flowering Time 9–10 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 500 g/m2

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Gelato

Gelato weed strain American genetics

Overview: Gelato, aka Larry Bird or Gelato 42, is a cookies marijuana strain from the West Coast with aromas reminiscent of an ice-cream shop. An All-American cross, Gelato was created with Sunset Sherbet and Thin Mints GSC genetics. Growing Gelato feminized seeds may take some skill for the best results, but they offer high yields, top quality, incredible potency, and delicious flavors in return. Up to 21% THC.

Flowering Time 8–10 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 18–21 oz/m2

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MAC

MAC strain weed seeds USA

Overview: MAC, which stands for Miracle Alien Cookies, is an indica-leaning hybrid with extraordinarily dense and resinous buds. This American strain of marijuana is a best-seller in dispensaries across the nation. MAC feminized seeds grow into short plants with large yields. MAC weed is liberally coated in trichomes with a sweet smell and flavor like sour cherry yogurt. The effects are very powerful and promote feelings of well-being with clear-headed euphoria. 23–27% THC.

Flowering Time 8–9 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 600 g/m2

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Granddaddy Purple

Granddaddy Purple aka GDP marijuana strain

Overview: Granddaddy Purple, aka GDP, is among the best purple strains of weed born in the USA. This NorCal indica is a hybrid of Purple Urkle, a West Coast strain known for its beautiful purple buds, and Big Bud, a reliable high-yielding weed plant. As a result of the cross, GDP yields large amounts of purple-colored buds with magnificent quality and potently sedative effects. GDP feminized seeds are easy to grow and adapt well to most climates. Up to 23% THC.

Flowering Time 9 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 14–17 oz/m2

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Strawberry Cough

Strawberry Cough American weed strain seeds

Overview: Strawberry Cough is an American marijuana strain best known for its extra-fruity smell and taste akin to ripe strawberries. This award-winning sativa hybrid is a favorite of those who demand the best flavors from cannabis strains. Strawberry Cough feminized seeds become thick and bushy plants that are easy to cultivate and yield averagely. The effects of Strawberry Cough are focused and energetic. Up to 25% THC.

Flowering Time 10–11 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 14 oz/m2

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Bubba Kush

Bubba Kush American cannabis genetics

Overview: Bubba Kush is a heavy indica strain from the US popularized on the West Coast. Bubba Kush has a reputation for being powerfully sedating, making it a perfect choice for users of medical cannabis. Bubba Kush buds are compact and resinous with hashy scents and flavor profiles. The plants grow squat in stature with broad leaves and densely-packed flowers. 15–20% THC.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 500 g/m2

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NYC Diesel

NYC Diesel Marijuana Strain Seeds

Overview: NYC Diesel is an appropriately named marijuana strain from the East Coast with chunky flowers that reek of diesel fuel. These stinky and potent buds deliver a long-lasting high with even feelings of cerebral euphoria and knockout body stone. NYC Diesel feminized seeds grow into large, vigorous female plants that produce heavy harvests for patient growers. 19% THC.

Flowering Time 10–12 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 16–18 oz/m2

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Green Crack

Green Crack USA weed seeds

Overview: Green Crack, aka Cush, is an American sativa strain named for its intensely energetic high. It has sweet and skunky flowers that glisten in trichomes. Green Crack feminized seeds are an ideal choice for beginner growers due to the strain’s vigor, natural resilience, and rewarding yields in a range of climates. Up to 22% THC.

Flowering Time 10 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 18–21 oz/3x3ft

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Do-Si-Dos

Do-Si-Dos Cannabis Strain US

Overview: Do-Si-Dos, aka Dosi Doe or Dosi, is a famous US indica cross of OG Kush Breath and Face Off OG. Do-Si-Dos weed has excellent bag appeal and severe potency reaching nearly 30% THC. It smells pungent, sweet, and earthy with great flavors to match. The effects are heavy hitting in the body. Do-Si-Dos feminized seeds are easy to cultivate as the plants stay short in stature and do not require expert care.

Flowering Time 8–10 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 400–500 g/m2

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Purple Haze

Purple Haze cannabis strain US breeder seeds

Overview: Purple Haze is an old-school sativa strain from the Emerald Triangle with widespread popularity due to the Jimi Hendrix song of the same name. Purple Haze marijuana is known for its trippy psychoactive effects that inspire creativity. The purple buds are covered in trichomes and exude a sweet exotic fragrance. Purple Haze plants thrive outdoors while performing remarkably in an indoor hydroponic setup as well. 18% THC.

Flowering Time 8–10 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 21 oz/m2

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Best Autoflower American Strains

Zkittlez Auto

Zkittlez Autoflowering Seeds USA

Overview: Zkittlez Auto is an autoflower (non-photoperiod) version of esteemed American cannabis strain, Zkittlez. It is one of the most sweet-tasting autoflower strains on the market. Zkittlez Auto feminized seeds become fairly short plants with great vigor and high production in just 90 days from seed to maturity. The end result is supremely potent with 21–24% THC.

Flowering Time 90 days
Brand Seedsman
Pack Size 1–100 seeds
Yield 400–500 g/m2

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Bruce Banner Auto

Bruce Banner strain autoflower seeds American

Overview: Bruce Banner Auto is an autoflower version of the mighty Bruce Banner strain from Colorado. These massive buds are sticky, delicious, and unusually potent. Bruce Banner Auto seeds grow shorter, bushier, and faster than the original strain, making it generally easier for beginners and to those who want a quicker harvest with a small footprint. Up to 25% THC.

Flowering Time 8–10 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 18 oz/m2

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Girl Scout Cookies Auto

Girl Scout Cookies Autoflower Fem Seeds USA

Overview: Girl Scout Cookies Auto is an autoflower version of the legendary Girl Scout Cookies marijuana strain from the San Francisco Bay Area. Girl Scout Cookies marijuana is renowned worldwide for its exotic quality. Girl Scout Cookies Auto feminized seeds grow into short female plants that develop highly potent and resinous buds with the signature cookie aroma and flavor. 20–22% THC.

Flowering Time 8–9 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 500–600 g/m2

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Trainwreck Auto

Trainwreck Auto West Coast USA Marijuana Strain

Overview: Trainwreck Auto is an autoflower plant bred from the acclaimed NorCal strain Trainwreck. This low-maintenance weed strain is perfect for beginners and outdoor growers due to its small size, high yields, and mold resistance. Trainwreck Auto has a life cycle of 10–13 weeks. When fully mature, its lime green buds are dense and sticky with resin. The effect is nearly tranquilizing and can be a source of great relief to medical cannabis users.

Flowering Time 75–90 days
Brand Humboldt Seed Co.
Pack Size 10 seeds
Yield High

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Purple Kush Auto

Purple Kush Autoflower American Weed Seeds

Overview: Purple Kush Auto is an autoflower version of one of the best Kush strains in America, Purple Kush. Purple Kush Auto buds have a beautiful purple color and thick resin coating that’s sure to impress any indica lover. Its calming effects allow for a deep sense of relaxation. Purple Kush Auto seeds become plants with a bushy indica structure and grow only 1–2 feet tall. 18% THC.

Flowering Time 10 weeks
Brand Homegrown
Pack Size 4/8/12/24 seeds
Yield 12–14 oz/m2

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Gorilla Glue #4 Auto

Gorilla Glue #4 Autoflower Cannabis Seeds USA

Overview: Gorilla Glue #4 Auto is an autoflowering take on the award-winning US strain Gorilla Glue, named for its gluey resin. Gorilla Glue marijuana has a pungent sour fragrance and provides strong euphoric yet relaxing effects. Gorilla Glue #4 Auto performs well grown indoors or outdoors and produces high yields of dank weed. 18–24% THC.

Flowering Time 8–9 weeks
Brand Blimburn
Pack Size 1–100 seeds
Yield 400–600 g/m2

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Sour Diesel Auto

Sour Diesel Autoflower Humboldt Seeds America

Overview: Sour Diesel Auto is a autoflower version of the iconic American weed strain Sour Diesel. Its has the classic sour gas aroma and flavor that Cali tokers know and love. Sour Diesel Auto seeds take between 75–85 days from seed to harvest. The plants are easy to grow and have a fair resistance to cannabis mold despite the density of its buds. The effects of Sour Diesel Auto promote energy and mental stimulation.

Flowering Time 75–85 days
Brand Humboldt Seed Co.
Pack Size 5/10 seeds
Yield High

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