22 Best Medical Marijuana Strains to Grow: Seed Guide

Top Best Medical Marijuana Strains Cannabis Seed Guide

Explore 22 of the best medical marijuana strains to grow—for sale in feminized and autoflowering seeds. This buyers’ guide to medicinal cannabis genetics covers a diverse range of weed strains, each featuring distinct potency levels and cannabinoid profiles, including high CBD, THC, CBG, CBDV, and THCV. Whether you’re a caretaker or homegrower, this guide provides you with the top selections for medical marijuana seeds online. Every strain listed is available for immediate shipment to all fifty states of the USA, with fast and discreet domestic delivery.


CBG Relief Auto

CBG Relief Auto by Seedsman

Seedsman’s CBG Relief Auto is a groundbreaking autoflowering strain named for its high CBG, or cannabigerol, content—a novel cannabinoid gaining substantial attention. The strain’s unique makeup possesses virtually no THC or CBD, making it an entirely legal choice in many countries. CBG Relief Auto seeds flourish into short, Christmas-tree-style plants with robust branches, growing to maturity within 8 to 10 weeks from seed. Despite its moderate yield of 350–450 g/m2, it compensates growers with aromatic buds featuring an appealing floral-like terpene profile. A testament to cannabis innovation, CBG Relief Auto presents growers with the opportunity to expand their horizons in the growing world of medicinal marijuana.

Flowering Time 8–10 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 350–450 g/m2
THC <1%
CBD <1%

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Runtz Muffin

Runtz Muffin by Barney's Farm

Runtz Muffin, a product of Barney’s Farm, is a prolific and easy-to-cultivate indica strain, recognized for its substantial medicinal qualities. This potent cannabis offspring, resulting from a careful cross of Zkittlez, Gelato, and Orange punch, boasts an extreme THC content of 29%. A feast for the senses, Runtz Muffin’s dense buds feature hints of purple and deep green, exhaling enticing sweet-scented notes reminiscent of a childhood candy store. Runtz Muffin feminized seeds mature into medium-height plants that are manageable for any level of grower, thriving both indoors and outdoors. Medicinally, this strain is prized for its capacity to deliver rapid relief from stress and anxiety, promoting a state of serene tranquility and positivity.

Flowering Time 8–9 weeks
Brand Barney’s Farm
Pack Size 1/3/5/10 seeds
Yield 550–600 g/m2
THC 29%
CBD Low

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CBDV 1:1 Auto

CBDV 1:1 Auto by Seedsman

Seedsman CBDV:CBD 1:1 Auto is an innovative medical cannabis strain highly concentrated with the non-psychoactive cannabinoids CBDV and CBD, while maintaining incredibly low THC levels, less than 0.3%. This strain, constituted by 75% sativa and 25% indica genetics, was bred for high yields within short life-cycles, harmonizing with both indoor and outdoor environments. Indoor plants mature within a swift 9–10 week period, while its short lifespan outdoors allows for multiple harvests annually. Emanating a fresh fragrance of pine and balsam, this strain excels with an approximate 1:1 CBDV to CBD ratio that far surpasses THC and other cannabinoids. Embodying an incredibly calming, non-psychoactive effect, CBDV 1:1 Auto serves as an ideal choice for medicinal marijuana users seeking mind and body relaxation.

Flowering Time 9–10 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 350–450 g/m2
THC <0.3%
CBD 5–10%

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Charlotte’s Angel CBD

Charlotte's Angel CBD by Dutch Passion

CBD Charlotte’s Angel is a popular therapeutic cannabis strain from Dutch Passion, offering a high CBD content and negligible levels of THC. This sativa-dominant cultivar is a unique blend of Dutch Charlotte and Red Angel CBD, delivering high yields after flowering for 9 to 12 weeks. Emitting a delightful herbal aroma with undertones of pine and diesel, the buds boast CBD levels averaging 15%, while the THC content is a mere 0.7% average, ensuring patients can medicate without the risk of getting high. Additionally, substantial resin production makes CBD Charlotte’s Angel an excellent choice for producing high-CBD, low-THC concentrates. Enjoyable even for recreational smokers looking for a satisfying experience without getting high, this strain not only relaxes the body but also promotes feelings of well-being and calm, providing significant anti-anxiety properties.

Flowering Time 9–12 weeks
Brand Dutch Passion
Pack Size 1/3/5/10 seeds
Yield 400–500 g/m2
THC 0.7%
CBD 15%

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Northern Lights Auto

Northern Lights Auto by Seedsman

Northern Lights Auto, a potent autoflowering weed strain from Seedsman, is a product of crossing the legendary Northern Lights with ruderalis. This indica-dominant hybrid displays hearty resistance to common plant diseases, fungi, and pests while producing high THC levels of up to 23%. With its straightforward cultivation, requiring moderate levels of fertilizer, this strain yields well both indoors and outdoors, with outdoor plants capable of up to two harvests per season. Its buds reveal a fusion of fruity sweetness and earthy pine essence, coupled with a hint of sour plum jam. Its profound effect of mental relaxation is amplified by a strong body sensation, making it an excellent medical cannabis strain for pain relief and stress management.

Flowering Time 55–60 days from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 500 g/m2
THC 23%
CBD 0.5%

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Harlequin

Harlequin by ILGM

Harlequin has carved out a reputation as a medicinal marvel in the cannabis community, boasting a sativa dominance that delivers an invigorating yet gentle high suitable for daytime use. With its rich tapestry of genetics—from Swiss sativa to Nepali indica—Harlequin offers a symphony of therapeutic effects, championing high CBD levels that make it a go-to for pain and anxiety relief without the intense psychoactivity. Cultivators appreciate Harlequin for its ability to produce heavy yields and adapt well to both soil and hydroponic setups, with a preference for a controlled, moderate climate. Boasting a rich terpene profile that combines earthiness with a hint of tropical mango and a spicy, pine-flavored smoke, Harlequin is as pleasing to the senses as it is therapeutically effective.

Flowering Time 8–9 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 14–17 oz/plant
THC Up to 7%
CBD 10–15%

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Zkittlez Auto

Zkittlez Auto by Seedsman

Zkittlez Auto emerges as a standout sativa-dominant strain, offering a confectionary symphony of sweet, fruity flavors reminiscent of the iconic candy. This robust autoflowering variant, bred from Zkittlez and Fruit Kush Auto, thrives vigorously, indulging in high nutrient uptake and ample hydration. Despite its manageable stature, rarely breaching four feet, Zkittlez Auto is a bountiful producer, yielding 400–500 g/m2 indoors and a slightly higher yield outdoors. Indoor growers are advised to implement proper odor control to contain its pervasive sweet berry fragrance. Touting a 21–24% THC content, its buds promise a well-rounded, euphoric high that caters to both social and solitary relaxation, with medicinal benefits that include pain relief, nausea, insomnia, depression, and appetite stimulation.

Flowering Time 90 days from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 400–500 g/m2
THC 21–24%
CBD <1%

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Doctor Seedsman CBD 30:1

Doctor Seedsman CBD 30:1 by Seedsman

Doctor Seedsman CBD, with its groundbreaking CBD:THC ratio of 30:1, emerges as a pioneering force in medicinal cannabis, delivering therapeutic relief without any psychoactivity. A testament to meticulous breeding, this strain boasts a high 20% CBD content while keeping THC levels below 1%. Its sativa dominance hails from CBD Asia genetics, renowned for its high CBD, which thrives without the need for intense inbreeding to stabilize its medicinal properties. Growers can anticipate a robust, squat plant that prospers indoors and out, yielding dense, resin-coated buds after 8 to 9 weeks of flowering. With an aromatic profile combining pine and ginger, Doctor Seedsman CBD offers a profoundly relaxing experience, ideal for patients seeking physical relief without impairing their mental clarity.

Flowering Time 8–9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 450–600 g/m2
THC <1%
CBD 20%

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Purple Punch Auto

Purple Punch Auto by Barney's Farm

Purple Punch Auto is a highly therapeutic, indica-dominant autoflowering marijuana strain, bred by fusing Purple Punch and Critical Auto. This easy-to-grow strain blossoms beautifully in both indoor and outdoor environments, growing to a short height of 2–3 feet and completing its life-cycle within a swift 50–60 days from seed. It’s multi-branched structure contributes to impressive yields—up to 350 g/m2 indoors and a remarkable 400 g/plant outdoors. Purple Punch Auto boasts buds that are both dense and glittering with resin, carrying an aroma and flavor that harks back to warm apple pie with notes of clove. In addition to its 18% THC content, the weed offers a comforting sense of euphoria and physical relaxation, proving particularly effective as a stress-reliever and medicinal aid for various conditions.

Flowering Time 50–60 days from seed
Brand Barney’s Farm
Pack Size 1/3/5/10 seeds
Yield 350 g/m2
THC 18%
CBD 1%

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Peyote Wifi CBD 2:1

Peyote Wifi CBD 2:1 by Seedsman

Peyote Wi-Fi CBD 2:1, a tranquil medical marijuana strain, was cultivated through a combination of Peyote Purple and WiFi OG crossed with the high-CBD Candida phenotype, Seedsman CBD #2. This plant inherits its caregiver properties from its parents, yielding twice the CBD (12–14%) compared to its THC content (6–8%), essentially reducing the psychoactive effects. Peyote Wi-Fi CBD 2:1 weed helps to reduce anxiety and induce relaxation while also alleviating symptoms of pain, depression, glaucoma, and appetite loss. With a roughly 65-day flowering period and stability in various climates and environments, Peyote Wi-Fi CBD 2:1 is as rewarding to cultivate as it is medicinal.

Flowering Time 8–10 weeks
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 450–600 g/m2
THC 6–8%
CBD 12–14%

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Red Pure CBD Auto

Red Pure CBD Auto by Sweet Seeds

Red Pure CBD Auto, a therapeutic cannabis strain rich in CBD, was developed by hybridizing Sweet Pure CBD and Red Poison Auto. Predominantly indica, it showcases a poignant central stem and shorter lateral branches typical to its indica lineage. Thriving in various settings, it peaks at three feet and yields 450–500 g/m2 indoors within nine weeks from germination, while outdoor yields vary between 30–100 g/plant. Aesthetic appeal lies in the striking red-hued buds present in 95% of the plants, which exude sweet, earthy aromas with hints of pine, cypress, and berries. With remarkably low THC levels at 0.4–0.5% and an elevated CBD content reaching 15–17%, Red Pure CBD Auto delivers potent calming effects perfect for alleviating anxiety without a psychotropic high.

Flowering Time 9 weeks from seed
Brand Sweet Seeds
Pack Size 3/5 seeds
Yield 450–500 g/m2
THC 0.4–0.5%
CBD 15–17%

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LA Confidential

LA Confidential by ILGM

L.A. Confidential, a renowned medicinal strain with an 80/20 indica dominance, stands out for its heavy THC content and effectiveness against chronic pain and mood disorders. Its genetics, a cross between Afghani and OG LA Affie, ensure a powerful euphoric and relaxing high, making it a go-to for relief from insomnia and anxiety. This strain’s ease of growth from feminized seeds, coupled with its inviting earthy and piney aroma, makes it both a practical and pleasant choice for therapeutic cultivation. Its sedative qualities also make it popular among those seeking solace from stress and depression. With its easy cultivation and robust medical benefits, L.A. Confidential remains a top contender in the West Coast cannabis scene.

Flowering Time 6–8 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 14–17 oz/plant
THC Up to 25%
CBD Low

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Blackberry Kush CBD Auto

Blackberry Kush CBD Auto by Dutch Passion

CBD Auto Blackberry Kush is an exceptional purple, indica-dominant CBD-rich autoflower, a cross between Dutch Passion’s CBD Charlotte’s Angel and Auto Blackberry Kush. It possesses a unique terpene blend, boasting an earthy, fruity aroma and taste with a strong hint of forest fruit flavors. Notably, this purple strain displays a THC content below 1%, making it an ideal choice for both medicinal and recreational users seeking a non-psychoactive high. Easy to cultivate, CBD Auto Blackberry Kush thrives in both small indoor spaces or outdoors in optimal summer conditions, offering dense, resinous buds ripe in approximately 10–13 weeks from seed. Its high CBD content offers a soothing effect that’s recommended for relaxation and therapeutic usage.

Flowering Time 10–13 weeks from seed
Brand Dutch Passion
Pack Size 1/3/7 seeds
Yield 450 g/m2
THC <1%
CBD 15%

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Bubba Kush

Bubba Kush by Seedsman

Pre ’98 Bubba Kush, is a potent indica strain with legendary standing in the United States. The Seedsman version, bred from two mid-90s Bubba Kush varieties, aims to offer growers the truest version of this iconic strain. Famed for its robust, psychedelic-high and powerful sedative effects, it is highly recommended for medical users seeking a powerful stress-buster and pain-reliever. The plants are compact making them ideal for small cultivation spaces. Leaning toward its indica genetics, Bubba Kush has large leaves and yields uniquely structured buds that glisten with trichomes and express a full spectrum of colors. Its intense aroma of sweet hash and spice captivates the senses, while the potent effects—up to 24% THC—make this strain lose footing for daytime use but shine as a nocturnal remedy.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 450–600 g/m2
THC 15–20%
CBD Low

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Pink Kush CBD 30:1 Auto

Pink Kush CBD 30:1 Auto by Seedsman

Pink Kush CBD Auto is a 90% indica strain that marries Pink Kush CBD Auto and Pink Afghan CBD Auto. Aptly reflecting its name, this strain exhibits a lovely pink hue within its buds and offers a delightful scent of pine, damp forest, and subtle red fruits. As an autoflowering strain with a short life cycle of nine weeks, it’s adaptable to all environments, potentially yielding multiple harvests in warmer climates. Pink Kush CBD Auto feminized seeds produce buds that have a stunning CBD:THC ratio of 30:1, with notable CBD levels at 17% and marginal THC at 0.5%. The medicinal user will appreciate its gentle, relaxing body effects, perfect for those seeking relief without the psychoactive impact.

Flowering Time 9 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield Good
THC 0.5%
CBD 17%

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Cream & Cheese CBD 1:1

Cream & Cheese CBD 1:1 by Seedsman

CBD Cream and Cheese is a therapeutic marijuana strain that boasts an almost 1:1 THC:CBD ratio. Retaining the signature features of classic Cheese varieties, this new strain in Seedsman’s catalog packs an impressive CBD content of 18%, rendering it highly effective in treating a range of ailments. CBD Cream and Cheese has a flowering period of about nine weeks, and it thrives in all environments and mediums of growth. Its rich, unmistakable Cheese-scented aroma and taste are undiminished by its lack of classic cerebral effects—instead, it offers a relaxing bodily sensation, catering to both recreational and medicinal users alike. With its unusual profile, CBD Cream and Cheese sets itself apart as a unique, high-CBD strain that is certainly worth considering for patients needing relief and growers seeking diversity for their strain collections.

Flowering Time 9 weeks
Brand Seedsman
Pack Size 1–100 seeds
Yield 450–600 g/m2
THC 18%
CBD 18%

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Skywalker OG Auto

Skywalker OG Auto by Barney's Farm

Skywalker OG Auto, a creation by Barney’s Farm, is a highly potent autoflowering cannabis strain that boasts powerful medical properties. Flowering in just 70–75 days, this compact strain reaches up to four feet in height and produces an abundance of kushy flowers drenched in THC crystals. The combination of a robust 23% THC level and a 75% indica dominance delivers deeply tranquilizing effects, promising full body relaxation and mental clarity. Noted to stimulate mind expansion, Skywalker OG Auto weed commonly induces insightful realizations, making it a fine choice for patients seeking medicinal cannabis for mental wellness. This strain is recognized not only for its potent effects but also for its intense pine flavor and impressive yields.

Flowering Time 70–75 days from seed
Brand Barney’s Farm
Pack Size 1/3/5/10 seeds
Yield 450–500 g/m2
THC 23%
CBD Low

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Critical Purple Kush

Critical Purple Kush by Seedsman

Critical Purple Kush, primarily an indica strain with an 80% ratio, encapsulates the remarkability of its parents—Blueberry, Critical, and Peyote Purple. This high yielding strain can grow big with its substantial height of 8–10 feet when grown outdoors, yielding impressive 600–800 g/plant. However, its spindly branches will require support to bear the weight of their large, spongy purple buds. Blessed with diverse flavors of pineapple, forest fruits, subtly coupled with zesty lemon and skunky afternotes, it boasts high THC and low CBD. Recommended for medical usage due to its profound physical relaxing effects, Critical Purple Kush serves as an attractive option for patients seeking pain relief and relaxation.

Flowering Time 60–65 days
Brand Seedsman
Pack Size 1–100 seeds
Yield 600+ g/m2
THC High
CBD Low

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Cannatonic

Cannatonic by ILGM

Cannatonic is a perfectly balanced hybrid of MK Ultra and G13 Haze, exuding a delightful blend of earthy and citrusy aromas. Famous for its remarkable therapeutic properties, Cannatonic excels with high CBD levels, reaching up to 12%, and moderately low THC levels which peak at 6%. The carefully engineered genetic combination gifts this strain with a highly potent and prolonged psychoactive relief—perfect for various health conditions. However, the cultivation of Cannatonic seeds can pose challenges for novice growers due to its susceptibility to mold and its potentially tall height. Despite this, its efficacy to naturally relieve various symptoms, combined with its energetic, mood-lifting effects make it a choice strain for medical marijuana patients.

Flowering Time 10–11 weeks
Brand ILGM
Pack Size 5/10/20 seeds
Yield 14–18 oz/plant
THC Up to 6%
CBD Up to 12%

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Gorilla Candy Auto

Gorilla Candy Auto by Seedsman

Gorilla Candy Auto is a fast-finishing, mold resistant strain ideal for beginners, boasting 80% indica genetics that yield a bushy, colorful plant. With a brief 56-day cycle, it’s not only easy to grow but also offers a sweet, earthy terpene profile. The strain’s potent effects, with THC levels ranging from 17–20%, offer medical users powerful pain relief and sedation, making it suitable for treating chronic pain and aiding sleep. Its striking colors during bloom add aesthetic appeal to its therapeutic benefits. Despite its potency, the pleasant caramel and fuel notes ensure a delightful tasting experience for those seeking both relief and flavor.

Flowering Time 8 weeks from seed
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 400–500 g/m2
THC 17–20%
CBD <1%

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Ice Cream Cake

Ice Cream Cake by Barney's Farm

Ice Cream Cake, an indica-dominant exotic hybrid descending from Wedding Cake and Gelato 33, is celebrated for its sweet, creamy flavor profile and robust therapeutic qualities. Its feminized seeds flourish both indoors and outdoors, with a swift flowering time and hearty yields, making it a top pick for growers. Boasting a high THC content, this strain’s relaxing effects are cherished by medical users for pain relief and stress reduction. The scent and taste are a rich blend of vanilla and earthy notes, with a tranquil, euphoric high that underscores its medicinal benefits. Ice Cream Cake’s ease of growth and potent relief potential make it a standout in any medicinal cannabis garden.

Flowering Time 55–65 days
Brand Barney’s Farm
Pack Size 1/3/5/10 seeds
Yield 600 g/m2
THC 20–25%
CBD Low

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Diet Durban THCV 1:1

Diet Durban THCV 1:1 by Seedsman

Diet Durban THCV:THC 1:1 is paving the way for cannabinoid-rich strains with its balanced and novel THCV to THC profile, highlighting a medical marvel with roughly 7% of each, tailored for medical users seeking clarity and appetite control. This swift-flowering, sativa-dominant hybrid, born from Thai landrace and Caprichosa Thai, adapts well to diverse growing conditions, albeit with care to avoid stress-induced male traits indoors. Indoor growers will appreciate the 9 to 10-week flowering period and the bountiful yields, while outdoor cultivators should monitor for favorable late-season weather. The weed’s aroma blends floral and spicy notes with a hint of citrus, enhancing its desirability. The combined cannabinoid profile offers a lucid and stimulating experience, ideal for patients needing an energetic cerebral effect without the munchies.

Flowering Time 9–10 weeks
Brand Seedsman
Pack Size 1/3/5/10 seeds
Yield 450–600 g/m2
THC 14%
CBD 2%

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Jared Cox profile image

Jared Cox is the author behind Mold Resistant Strains. He is a cannabis grower, breeder, and archivist of seeds. His work across several disciplines extensively covers cannabis genetics, cultivation, processing, and sales.

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